Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib
نویسندگان
چکیده
منابع مشابه
An Overview of Bortezomib-Induced Neurotoxicity
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Proteasome inhibition forms the cornerstone of antimyeloma therapy. The first-in-class proteasome inhibitor, bortezomib, either alone or in combination with other chemotherapeutic agents, induces high overall response rates and response qualities in patients with clinically and molecularly defined high-risk disease. However, resistance to bortezomib and neurotoxicity associated with the treatme...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-34507-3